Research

The ICENI Centre acts a hub for surgical research in the Eastern region, specialising in minimally invasive surgical techniques throughout all surgical disciplines. Through collaboration with partner centres, large scale clinical studies can be undertaken to assess new techniques and treatments that enhance patient benefits.

 

 

Recent ICENI publications:

2015-16

S.P. Vasudevan, A.B. Cresswell, J.M. Wright, M. Rees, D. Stiff, A. Wordley and R.W. Motson :
Close collaboration between local and specialist multidisciplinary teams allow ‘fast tracking’ of patients with colorectal liver metastases.

Colorectal Disease, 15: 1253-1256, 2013.


M.Eddama, L. Totton, S.P. Vasudevan, R.W. Motson :
In women who sustained a third degree tear, can we predict further tears in subsequent deliveries?

International Journal of Surgery, 11 : 629, 2013 (abstract).


M. Eddama, P. Haylock-Vise, N.J. Smart, T.H.A. Arulampalam and R.W. Motson :
Does a dedicated laparoscopic emergency theatre have an effect on the proportions of operations performed laparoscopically?

International Journal of Surgery, 11 : 715, 2013 (abstract).


Navaratnam, R. Ariyaratnam, N. Smart, M. Parker, R.W. Motson and T.H.A. Arulampalam :
Incisional hernia rate after laparoscopic colorectal resection is reduced with standardisation of specimen extraction.

Annals of the Royal College of Surgeons of England, 97 : 190-195, 2015.


H. MacKenzie, M. Ni, D. Miskovic, R.W. Motson, M. Gudgeon, Z. Khan, R. Longman, M.G. Coleman and G.B. Hanna :
Clinical validity of consultant technical skills assessment in the English National Training Programme for laparoscopic colorectal surgery.

British Journal of Surgery, 102 : 991-997, 2015.


R.W. Motson and A. Lacy :
The rationale for trans-anal total mesorectal excision.

Diseases of Colon and Rectum, 58 : 911-913, 2015.


Training Manual in Minimal Access Surgery. N. Francis, A. Fingerhut, R. Bergamaschi and R. Motson, Editors.

Springer, London, pp 214, 2015.


R.W. Motson, M.H. Whiteford, R. Hompes, M. Albert and W.F.A. Miles :
Current status of trans-anal total meso-rectal excision (TaTME) following the 2nd international summit conference.

Colorectal Disease. 18 : 13-18, 2016.


M. Sbaih, T.H.A.Arulampalam and R.W. Motson :
Rate of skill acquisition in the use of a robotic laparoscope holder (Freehand®).

Minimally Invasive Therapy and Allied Techniques, 25 : 196-202, 2016.


Mangano and R.W. Motson :
Evidence-based analysis and effectiveness of self-expanding metallic stents as abridge to surgery versus emergency surgery for colon cancer.

Future Oncology, 17 :1957-1960, 2016.


Mortality of emergency abdominal surgery in high-, middle- and low-income countries.

GlobalSurg Collaborative.

Br J Surg. 2016 Jul;103(8):971-88. doi: 10.1002/bjs.10151.


Virtual Reality Training in Laparoscopic Surgery: A Systematic Review and Meta-analysis

Alaker M, Wynn GR, Arulampalam THA.

Int J Surg. 2016 in press 2016 May;29:85-94. doi: 10.1016/j.ijsu.2016.03.034. Epub 2016 Mar 15


What Happens When We Don’t Operate?

Bethune R, Sbaih M, Brosnan C, Arulampalam THA.

Ann R Coll Surg. 2016;98:409-412


A Research Agenda for Minimally Invasive Surgery for the European Surgeon: Delphi Study

Francis N, Kazaryan A, Pietrabissa A, Goitien D, Yannkopoulou E, Agresta F, Khatkov I, Schulze S,
Arulampalam THA, Tomulescu V, Kim Y-W, Taragona E, Zaninotto G
On behalf of the European Association of Enoscopic Surgeons

Surg Endosc 2016 submitted


Global Surgery in the 21st Century: Current Problems and Potential Solutions.

McDermott F, Kelly ME, Warwick A, Arulampalam TH, Brooks AJ, Gaarder T, Cotton B, Winter D.

Br J Surg. 2015;103:165-169.


Review of Neoadjuvant Chemotherapy Alone in Locally Advanced Rectal Cancer.

Jalil O, Claydon L, Arulampalam THA.

J Gastrointest Canc. 2015 46:219-236 doi: 10.1007/s12029-015-9739-7.


What Happens When We Don’t Operate?

Bethune R, Arulampalam THA.

Editorial – Colorectal Dis. 2015 17:279-280 doi: 10.1111/codi.12828.


2014-15

R Zorron , H Phillips , GR Wynn, C Fernandes, R Pessoa, R Vassallo, D Coelho : Transanal retrograde total mesorectal excision: preliminary series of 9 patients.
J Minim Access Surg. 2014;10:144-50.


GP São Julião, FM Smith, CP Macklin, ML George, GR Wynn : Opinions have changed to the management of rectal cancer patients with a clinical complete response to neoadjuvant chemoradiotherapy.
Colorectal Disease. 2014;16:392-4.


A Navaratnam, R Ariyaratnam, N Smart, M Parker, RW Motson and THA Arulampalam : Incisional hernia rate after laparoscopic colorectal resection is reduced with standardisation of specimen extraction.
Annals of the Royal College of Surgeons of England, 97 : 190-195, 2015.


AQ Howard, S Sinha, A Edwards, I Ahmad, CM Backhouse, J Davies. Successful laparoscopic repair of refractory type Ia endoleak after endovascular abdominal aortic aneurysm repair.
Journal of Vascular Surgery. 2015; 61(1):275-9.


Behrenbruch C, Ryan J, Lynch C, Wynn GR, Heriot A. Complete clinical response to neoadjuvant chemoradiotherapy for rectal cancer: an Australasian perspective.
Australian and New Zealand Journal of Surgery, 2015;85:103-4


RW Motson and A Lacy : The rationale for trans-anal total mesorectal excision.
Diseases of Colon and Rectum, 58 : 911-913, 2015.


Training Manual in Minimal Access Surgery. N. Francis, A. Fingerhut, R. Bergamaschi and R. Motson, Editors.

Springer, London, pp 214, 2015.


SK Somasundaram, L Massey, D Gooch, J Reed, D Menzies : Laparoscopic splenectomy is the emerging gold standard even for massive spleens.
Annals Royal College of Surgeons England 2015; 97: 345–348


AQ Howard, PC Bennett, I Ahmad, SA Choksy, SI Mackenzie, CM Backhouse. Introduction of laparoscopic abdominal aortic aneurysm repair.
British Journal of Surgery. 2015 :368-74.


O. Jalil O, L. Claydon , T.H.A. Arulampalam. :Review of Neoadjuvant chemotherapy in locally advanced rectal cancer .
Journal of Gastrointestinal Cancer 2015;46: 219-236.


R. Mittal , T.H.A. Arulampalam. : Screening and prevention of extra colonic cancer in Hereditary Non-Polyposis Colorectal Cancer.
GI Surgery Annual, Eds. Chattopadhyay and Sahni, Indian Association of Surgical
Gastroenterology, 2015.


F. McDermott , M.E. Kelly, A. Warwick, T.H.A. Arulampalam, A.J. Brooks, T. Gaarder, B. Cotton, D. Winter. : Global Surgery in the 21st Century: Current Problems and Potential Solutions.
British Journal of Surgery Accepted for publication BJS0679 August 2015.


H. MacKenzie, M. Ni, D. Miskovic, R.W. Motson, M. Gudgeon, Z. Khan, R. Longman, M.G. Coleman and G.B. Hanna : Clinical validity of consultant technical skills assessment in the English National Training Programme for laparoscopic colorectal surgery.
British Journal of Surgery, (in press)


The use of laparoscopic subtotal cholecystectomy for complicated cholelithiasis.

Philips JA, Lawes DA, Cook AJ, Arulampalam TH, Zaborsky A, Menzies D, Motson RW.
Surg Endosc. 2008 Jul;22(7):1697-700. Epub 2007 Dec 11.
PMID: 18071804 

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Training higher surgical trainees in laparoscopic common bile duct exploration.

Tutton MG, Pawa N, Arulampalam TH, Motson RW.

World J Surg. 2010 Mar;34(3):569-73. doi: 10.1007/s00268-009-0335-5.
PMID: 20063096

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A retrospective audit comparing outcomes of open versus laparoscopic repair of umbilical/paraumbilical herniae.

Solomon TA, Wignesvaran P, Chaudry MA, Tutton MG.

Surg Endosc. 2010 Dec;24(12):3109-12. doi: 10.1007/s00464-010-1097-8. Epub 2010 May 20. No abstract available.
PMID: 20490566 

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Laparoscopic colorectal cancer surgery in obese patients.

Singh A, Muthukumarasamy G, Pawa N, Riaz AA, Hendricks JB, Motson RW.
Colorectal Dis. 2011 Aug;13(8):878-83. doi: 10.1111/j.1463-1318.2010.02348.x. Epub 2010 Jun 10.
PMID: 20553315 

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Laparoscopic total mesorectal excision following long course chemoradiotherapy for locally advanced rectal cancer.

Motson RW, Khan JS, Arulampalam TH, Austin RC, Lacey N, Sizer B.
Surg Endosc. 2011 Jun;25(6):1753-60. doi: 10.1007/s00464-010-1353-y. Epub 2011 May 2.
PMID: 21533976

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Enhanced recovery program following colorectal resection in the elderly patient.

Pawa N, Cathcart PL, Arulampalam TH, Tutton MG, Motson RW.

World J Surg. 2012 Feb;36(2):415-23. doi: 10.1007/s00268-011-1328-8.
PMID: 22146943 

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A survey of smartphone and tablet computer use by colorectal surgeons in the UK and Continental Europe.

Smart NJ.

Colorectal Dis. 2012 Sep;14(9):e535-8. doi: 10.1111/j.1463-1318.2012.03161.x.
PMID: 22747977

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Close collaboration between local and specialist MDTs allow "fast-tracking" of patients with colorectal liver metastases.

Vasudevan SP, Cresswell AB, Wright JM, Rees M, Stiff D, Wordley A, Motson RW.

Colorectal Dis. 2013 Jun 22. doi: 10.1111/codi.12323. [Epub ahead of print]
PMID: 23790093 

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Commercial Research

Whether you are bringing a new device to market and wish to gather data on its safety and efficacy prior to regulatory approvals or conducting post market studies to determine further indications, clinical benefits or thorough health technology appraisal to provide evidence of clinical and economic outcome superiority the ICENI Centre can help.

With access to the PMI Clinical trials unit and over two million patients in our partnership hospitals, the ICENI Centre is your link to surgical talent, trials infrastructure and commercial expertise that can help you to frame your research questions and then conduct studies in order show the potential of your unique devices.

For more information and to discuss collaborations please contact Tan Arulampalan